Articular cartilage defects in a rabbit model, retention rate of periosteal flap cover

Using Xenogenic (Calf Foetal) Osteochondral Transplantation for Articular Cartilage Defect in Rabbit Model

Background: The destruction of articular cartilage is the major cause of articular problems. The articular cartilage has little repair postertial due to lack of perichondrium and direct blood circulation. It is, therefore important to consider this phenomena in surgical treatments. One of the articular cartilage reconstructive surgeries is using Osteo-Chondral graft. The main purpose of this re...

Static indentation test for neocartilage surface hardness in repair of periosteal articular cartilage defects.

The objective of this study was to determine whether hardness of the superficial layer is a useful parameter to characterise cartilage produced by periosteal neochondrogenesis, using rabbit knee lesions as a model. A cartilage defect was created in the right hind knee of anesthetised young adult rabbits, and the defect was then covered with an autologous periosteal graft. At one and eight month...

the healing effect of bioglue in articular cartilage defect of femoral condyle in experimental rabbit model

Intra-articular injection of Torin 1 reduces degeneration of articular cartilage in a rabbit osteoarthritis model

OBJECTIVES Recent studies have shown that systemic injection of rapamycin can prevent the development of osteoarthritis (OA)-like changes in human chondrocytes and reduce the severity of experimental OA. However, the systemic injection of rapamycin leads to many side effects. The purpose of this study was to determine the effects of intra-articular injection of Torin 1, which as a specific inhi...

Evaluation of articular cartilage progenitor cells for the repair of articular defects in an equine model.

BACKGROUND We sought to determine the effectiveness of chondroprogenitor cells derived from autologous and allogenic articular cartilage for the repair of cartilage defects in an equine model. METHODS Cartilage defects (15 mm) were created on the medial trochlear ridge of the femur. The following experimental treatments were compared with empty-defect controls: fibrin only, autologous chondro...